OTHERS ANIMALS
Porcine Karyotyping
Detection of Chromosomal Abnormalities by Fluorescent Oligo-Banding
Pig production is highly competitive, and the sustainability of businesses is directly linked to their productivity and profitability. The prolificacy of animals is a major factor, as a below-average litter size results in significant economic losses. It is well known that chromosomal abnormalities affect the fertility of affected pigs. For example, nearly half of boars with fertility issues are affected, and the most common type of abnormality leads to an average litter size reduction of nearly 40%. Unlike in France, breeders in Quebec are not systematically tested to combat this hindrance to productivity.
A method developed at Université Laval with the support of MAPAQ allows for the evaluation and confirmation of porcine chromosome integrity. This technique is based on the principles of fluorescence in situ hybridization and enables the labeling of 96 specific regions using marked oligonucleotides. This process generates a unique barcode for each chromosome. Rearrangements are identified when the banding pattern is altered due to the deletion, duplication, or displacement of chromosomal fragments. The tool has been tested and validated, proving to be both effective and sensitive.
Development Team:
William Poisson, Alexandre Bastien, Isabelle Gilbert, Julien Prunier, and Claude Robert
Alpaca Colors
Alpaca colors are determined by genetic variations that influence the distribution of pigments in the coat. Our DNA tests identify these variations, providing a deeper understanding of color genetics within a breeding program.
These analyses offer precise information on the alleles present, making it easier to predict potential coat colors in offspring.
Other Animals
We also offer related molecular biology services, such as DNA extraction from tissues, hair, feces, saliva, etc., as well as PCR amplification, sequencing, genotyping, and more.
Feel free to contact us to discuss your needs and learn more about our various services.
For dairy cows, several genetic variants in milk proteins have been shown to influence milk curd formation and, consequently, cheese-making properties (reviewed by Jakob & Puhan, 1992; Ng-Kwai-Hang, 1998). We offer tests to detect specific genetic variants in the beta-lactoglobulin (BLG), kappa-casein (CSN3), and beta-casein (CSN2) genes.