Genes Affected: MC1R
Inheritance: Autosomal dominant
Mutation: CanFam3.1         chr5          g.63694460C>T c.790A>G
OMIA link: 001590-9615

Appropriate breeds for testing: Many breeds including Leonberger, Malinois

References:
Everts RE, Rothuizen J, van Oost BA. Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat color. Animal Genetics. 2000 Jun; 31(3):194-99. [PubMed: 10895310]
Schmutz SM, Berryere TG, Ellinwood NM, Kerns JA, Barsh GS. MC1R studies in dogs with melanistic mask or brindle patterns. J Hered. 2003 Jan-Feb; 94(1):69-73. [PubMed: 12692165]